Transformation Based Ensembles for Time Series Classification

Until recently, the vast majority of data mining time series classification (TSC) research has focused on alternative distance measures for 1-Nearest Neighbour (1-NN) classifiers based on either the raw data, or on compressions or smoothing of the raw data. Despite the extensive evidence in favour of 1-NN classifiers with Euclidean or Dynamic Time Warping distance, there has also been a flurry of recent research publications proposing classification algorithms for TSC. Generally, these classifiers describe different ways of incorporating summary measures in the time domain into more complex classifiers. Our hypothesis is that the easiest way to gain improvement on TSC problems is simply to transform into an alternative data space where the discriminatory features are more easily detected. To test our hypothesis, we perform a range of benchmarking experiments in the time domain, before evaluating nearest neighbour classifiers on data transformed into the power spectrum, the autocorrelation function, and the principal component space. We demonstrate that on some problems there is dramatic improvement in the accuracy of classifiers built on the transformed data over classifiers built in the time domain, but that there is also a wide variance in accuracy for a particular classifier built on different data transforms. To overcome this variability, we propose a simple transformation based ensemble, then demonstrate that it improves performance and reduces the variability of classifiers built in the time domain only. Our advice to a practitioner with a real world TSC problem is to try transforms before developing a complex classifier; it is the easiest way to get a potentially large increase in accuracy, and may provide further insights into the underlying relationships that characterise the problem

The Oswald Clergy Burnout Scale: reliability, factor structure and preliminary application among Australian clergy

This study assesses the Oswald Clergy Burnout Scale (OCBI), the psychometric properties of which have not been previously described. Analysis of responses from a large number (N  = 3,012) of ministers in charge of Australian congregations showed that the scale’s internal reliability was satisfactory, and that the scale could be represented by two factors, identified, respectively, as the personal and social aspects of burnout. This structure was supported by confirmatory factor analysis. Several demographic and job-related variables that might relate to burnout were regressed on the total, personal and social factor scores. Age is the predominant (negative) predictor of burnout as measured by the total scale and the personal factor scores. All variables predict burnout as measured by the social factor. However, in all models, the predictor variables account for no more than 5% of the total variance. These findings suggest that demographic factors and working conditions are poor predictors of burnout among clergy

A multidisciplinary approach to the implementation of non-pharmacological strategies to manage infant pain

Hills E., Rosenberg J., Banfield N., Harding C. A multidisciplinary approach to the implementation of non-pharmacological strategies to manage infant pain. Infant 2020; 16(2): 78-81. 1. Newborn infants are capable of experiencing pain. 2. Infants requiring specialist hospital care are likely to experience painful medical procedures. 3. Unmanaged pain has a long-lasting impact on an infant’s behaviour and physiological status

Diagnosis of antiphospholipid syndrome in routine clinical practice.

The updated international consensus criteria for definite antiphospholipid syndrome (APS) are useful for scientific clinical studies. However, there remains a need for diagnostic criteria for routine clinical use. We audited the results of routine antiphospholipid antibodies (aPLs) in a cohort of 193 consecutive patients with aPL positivity-based testing for lupus anticoagulant (LA), IgG and IgM anticardiolipin (aCL) and anti-ß(2)glycoprotein-1 antibodies (aß(2)GPI). Medium/high-titre aCL/aβ(2)GPI was defined as >99th percentile. Low-titre aCL/aβ(2)GPI positivity (>95(th )< 99(th) percentile) was considered positive for obstetric but not for thrombotic APS. One hundred of the 145 patients fulfilled both clinical and laboratory criteria for definite APS. Twenty-six women with purely obstetric APS had persistent low-titre aCL and/or aβ(2)GPI. With the inclusion of these patients, 126 of the 145 patients were considered to have APS. Sixty-seven out of 126 patients were LA-negative, of whom 12 had aCL only, 37 had aβ(2)GPI only and 18 positive were for both. The omission of aCL or aβ(2)GPI testing from investigation of APS would have led to a failure to diagnose APS in 9.5% and 29.4% of patients, respectively. Our data suggest that LA, aCL and aβ(2)GPI testing are all required for the accurate diagnosis of APS and that low-titre antibodies should be included in the diagnosis of obstetric APS

Total immersion: maps, landscape and memory

It has been argued that we live in a map immersed world, but that the ubiquity of maps may actually lead to their devaluation and perhaps, even a form of invisibility. This paper describes a project designed to share ideas about the value of maps and mapping with the people of the county of Kent (UK) during International Map Year (IMY). The project involved a team of geographers at Canterbury Christ Church University writing a series of articles on maps and landscape to celebrate the year, but also engage people with mapping

Data Catalog Series for Space Science and Applications Flight Missions

The main purpose of the data catalog series is to provide descriptive references to data generated by space science flight missions. The data sets described include all of the actual holdings of the Space Science Data Center (NSSDC), all data sets for which direct contact information is available, and some data collections held and serviced by foreign investigators, NASA and other U.S. government agencies. This volume contains narrative descriptions of data sets from geostationary and high altitude scientific spacecraft and investigations. The following spacecraft series are included: Mariner, Pioneer, Pioneer Venus, Venera, Viking, Voyager, and Helios. Separate indexes to the planetary and interplanetary missions are also provided

Editorial: Aftereffects in face processing

Editorial: The original aim of this special issue was to use aftereffects to highlight the different cognitive, perceptual, and neural representations of unfamiliar and familiar faces. Face aftereffects occur due to prolonged exposure to an adaptor face that causes a test face to take on the “opposite” characteristics (e.g., a normal face will appear compressed following adaptation to an expanded face, Webster and MacLin, 1999). The resulting papers went beyond this aim and have demonstrated the extensive potential for theoretical advancement that research on aftereffects can create

Visfatin reduces gap junction mediated cell-to-cell communication in proximal tubule-derived epithelial cells

Background/Aims: In the current study we examined if the adipocytokine, visfatin, alters connexin-mediated intercellular communication in proximal tubule-derived epithelial cells. Methods: The effects of visfatin (10-200ng/mL) on cell viability and cytotoxicity in HK2-cells were assessed by MTT, crystal violet and lactate dehydrogenase assays. Western blot analysis was used to confirm expression of Cx26, Cx40 and Cx43. The effect of visfatin (10-200ng/mL) on TGF-β1 secretion was confirmed by ELISA, and the effects of both TGF-β1 (2-10ng/mL) and visfatin (10-200ng/mL) on connexin expression were assessed by western blot. Functional intercellular communication was determined using transfer of Lucifer Yellow and paired-whole cell patch clamp electrophysiology. Results: In low glucose (5mM), visfatin (10-200ng/mL) did not affect membrane integrity, cytotoxicity or cell viability at 48hrs, but did evoke a concentration-dependent reduction in Cx26 and Cx43 expression. The expression of Cx40 was unaffected. At 48hrs, visfatin (10-200ng/mL) increased the secretion of TGF-β1 and the visfatin-evoked changes in connexin expression were mimicked by exogenous application of the pro-fibrotic cytokine (2-10ng/ml). Visfatin reduced dye transfer between coupled cells and decreased functional conductance, with levels falling by 63% as compared to control. Although input resistance was increased following visfatin treatment by 166%, the change was not significant as compared to control. The effects of visfatin on Cx-expression and cell-coupling were blocked in the presence of a TGF-β1 specific neutralizing antibody. Conclusions: The adipocytokine visfatin selectively evoked a non-toxic reduction in connexin expression in HK2-cells. The loss in gap-junction associated proteins was mirrored by a loss in functional conductance between coupled cells. Visfatin increased TGF-β secretion and the pattern of change for connexins expression was mimicked by exogenous application of TGF-β1. The effect of visfatin on Cx-expression and dye transfer were negated in the presence of a TGF-β1 neutralising antibody. These data suggest that visfatin reduces connexin-mediated intercellular communication in proximal tubule-derived epithelial cells via a TGF-β dependent pathway. © 2013 S. Karger AG, Base